美国海军下属“海豹”特种突击队队长沃特斯（布鲁斯·威利斯 Bruce Willis 饰）带领一支小分队前往非洲密林执行命令：把在当地进行紧急医护工作的莱娜医生（莫妮卡·贝鲁齐 Monica Bellucci 饰）营救出来。小分队很快找到了莱娜医生，但在最后关头莱娜医生提出要把这里的70个难民一起转移的要求，否则自己也不会离开。沃特斯犯难了，非洲原始丛林天险众多，而且有剧毒莫测的野生动物，小分队人数不够，如何带着70个老弱病残逃离？然而人道主义最终打了胜仗，这支小分队在前有丛林、后有追兵的情况下带领这浩浩荡荡几十人开始了转移的道路，一个接一个的士兵倒下，生命的价值在这里人人平等。Navy SEAL Lieutenant A.K. Waters and his elite squadron of tactical specialists are forced to choose between their duty and their humanity, between following orders by ignoring the conflict that surrounds them, or finding the courage to follow their conscience and protect a group of innocent refugees. When the democratic government of Nigeria collapses and the country is taken over by a ruthless military dictator, Waters, a fiercely loyal and hardened veteran is dispatched on a routine mission to retrieve a Doctors Without Borders physician, Dr. Lena Kendricks. Dr. Kendricks, an American citizen by marriage, is tending to the victims of the ongoing civil war at a Catholic mission in a remote village. When Waters arrives, however, Dr. Kendricks refuses to leave unless he promises to help deliver the villagers to political asylum at the nearby border. If they are left behind, they will be at the mercy of the enormous rebel army. Waters is under strict orders from his commanding officer Captain Bill Rhodes to remain disengaged from the conflict. But as he and his men witness the brutality of the rebels first-hand, they are won over to Dr. Kendricks' cause and place their lives at risk by agreeing to escort the villagers on a perilous trek through the dense jungle. As they move through the countryside on foot, Waters' team, experts at evasion and concealment, are inexplicably and ferociously pursued by an army of rebels. They are confounded until they discover that, among the refugees, is the sole survivor of the country's previous ruling family, whom the rebels have been ordered to eliminate at all costs. Waters and his small band of soldiers must weigh the life of one man against their own and the refugees they feel obliged to protect.
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