This series is a biography about the Queen of Castile, Isabella the Catholic. The second season will chronicle the period between 1474 and 1492: from her crowning to the conquest of Granada and the beginning of the journey of Christopher Columbus.Isabel's decision to take the Crown while Fernando is in Aragon angers him, a division that Carrillo is eager to use. Meanwhile, Diego Pacheco seeks support from Portugal and the nobles to dethrone Isabel in favor of Juana.